I had a problem "Unauthorized" in official twitter client for Mac. Tried several instal/reinstall. Deleted/Downloaded again from Apple App Store. It all didn't help. They seem to change something in authentication. So I've tried deleting all the config files in ~/Library/ Main solution that helped me: 1. Switch off the client. (be sure to Close an app) 2. Delete: ~/Library/Preferences/com.twitter.twitter-mac.plist.lockfile ~/Library/Preferences/com.twitter.twitter-mac.plist 3. Launch Twitter app and login from scratch. I have revoked access this twitter client too in my https://twitter.com/settings/applications but it seem to make no effect. Making similar actions to TweetDeck for Mac does not help. So it seems like problem is somewhere deeper. Hope it will help you solve similar issue.
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